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依托泊甙
貨號:T0132
產品名稱: 依托泊甙
英文名: Etoposide
CAS NO.: 33419-42-0
分子式: C29H32O13
分子量: 588.556590080261
產品品牌: targetmol
產品規格: 25mg
依托泊甙
依托泊甙抑制劑Etoposide is a semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.